A 28-year-old man developed gambling addiction and compulsive sexual behaviour during treatment with aripiprazole.
The man, who had a history of schizoid personality disorder, received aripiprazole [route not stated] at a dose of 15mg. Subsequently, he developed an addiction habit for gambling at casino slot machines. He had large gambling debts; hence, he requested to put him on a voluntary self-exclusion list. He then turned towards scratch card gambling. He described his gambling experience as a hypnotic state. He was refereed to an addiction unit. He was heterosexual with poor sexual activity before starting the therapy. During the aripiprazole therapy, he changed to a homosexual behaviour with hypersexuality, unprotected sex and sadomasochistic practices [durations of treatments to reaction onsets not stated].
Aripiprazole was ceased, and was changed to amisulpride. Two weeks later, his gambling addiction and compulsive sexual behaviour recovered. He returned to a heterosexual behaviour.
Reactions Weekly is the unique one-stop-shop for all your adverse drug reaction needs, bringing you up-to-the minute summaries of the world's adverse drug reaction news and published adverse drug reaction case reports. Reactions Weekly provides a weekly round-up of adverse drug reaction news including labelling changes, drug withdrawals due to safety issues, adverse reaction research and current issues in drug safety. Content is sourced from journals, scientific meetings, media releases, regulatory agency websites, and bulletins from the National Centers that participate in the WHO International Drug Monitoring Programme.