Central to a public health approach to gambling problems is early detection. Drawbacks of traditional screening efforts have reinforced the need for brief problem gambling screens particularly in time sensitive settings such as primary care. The only, existing primary care brief instrument is limited by its psychometric development and is not informed by contemporary gambling research. The Memphis Gambling Inventory (MGI) is a new problem gambling brief screen that assesses several dimensions of gambling behavior, cognition, motivation, and consequences. The current study evaluated the screening performance of the MGI's original 15-item pool. ROC analysis revealed a 3-item MGI that correctly classified 87% of at-risk gamblers. The MGI's items include one behavioral indicator, one gambling-specific cognitive distortion, and one consequence resulting from gambling. The MGI was associated with other measures of problem gambling and gambling behavior consequences. Implications for screening with the MGI are discussed.