This study introduced the combination of positive and negative factors in predicting problem gambling (PG) with the adaptation of Sharpe's biopsychosocial model of gambling behaviour (Sharpe, 2002). The participants consisted of 801 Taiwanese Chinese students and community individuals (Mean age = 25.36 years). In the proposed framework, gambling-urge mediated the relationship of negative psychological states, hope, gratitude, and personal-growth initiative with gambling-related cognitions. Meanwhile, gambling-related cognitions mediated the relationship between gambling-urge and PG among the Chinese. Path analyses provided support for this framework. The results evidenced the importance of gratitude in predicting PG among the Chinese via gambling-urge and gambling-related cognitions. In addition, hope in life (encompassing autonomy in devising plans for life goals and agency in thought processes) was found to have the same predictive pathway as gratitude on PG. Contrary to initial predictions, stronger personal-growth initiative predicted higher PG severity, gambling-related cognitions, and gambling urges. Implications and suggestions for future research are discussed.