The authors of this paper examines the relationship between casino-based gambling and crime, using routine activities theory as it applies to transnational crime. Crimes that are traditionally associated with casino-based gambling include organized crime, political corruption, money laundering, skimming by employees, loan-sharking, and various forms of street crime such as robbery, prostitution, check forgery, and drug dealing. Whereas such problems have long plagued casinos, they became magnified in an increasingly transnational world. Globilization has made possible the exchange of legitimate goods and services, but it has also made possible the transnational exchange of illicit goods and services. The paper's conclusions are focused on the role of policing in controlling such forms of transnational crime.